AlphaFold Protein Structure Database

Precomputed AlphaFold structure predictions for most known proteins.

Developer: Google DeepMind and EMBL-EBI

Commercial use OKFree for commercial use

Overview

Developer
Google DeepMind and EMBL-EBI
Commercial rights
Commercial OK
Commercial cost
Free commercially
Compute
Hosted service
Open weights
Yes
Last verified

Capabilities

Precomputed structure predictions. Input: a UniProt accession; output: the AlphaFold model with pLDDT/PAE - the fastest way to get a usable structure for a target with no crystal.

When to use it

Use to grab a target model instantly instead of folding it yourself. These are predictions with pLDDT confidence, not experimental structures, and low-pLDDT regions should not be treated as real conformations.

Input / Output

Input
a UniProt accession
Output
the AlphaFold model with pLDDT/PAE - the fastest way to get a usable structure for a target with no crystal

Compute

Hosted service. Other tools with this compute profile →

Commercial Licensing

Commercial rights — may a company use it?

Commercial use OK

Licence as writtenCreative Commons Attribution 4.0 International (CC BY 4.0)

The AlphaFold DB homepage and download page both state: 'Data is available for academic and commercial use, under a CC-BY-4.0 licence.'

Original sources — read on 15 Oct 2026
  1. alphafold.ebi.ac.uk
  2. alphafold.ebi.ac.uk/download

The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.

Commercial cost — is commercial use free of charge?

Free for commercial use

Free under CC BY 4.0 - note this is the database of predictions, which is licensed far more openly than the AlphaFold 3 weights.

Original sources — read on 15 Oct 2026
  1. alphafold.ebi.ac.uk/about

Price and rights are separate: this panel is about money, the panel above is about permission.

  • Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
  • Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
  • Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
  • Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.

Model Weights

Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.

Dependencies

Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.

Official References

Official site / repo
alphafold.ebi.ac.uk

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