IgGM

Generative model for antibody design that states commercial use is allowed.

Developer: Tencent AI4S

Commercial use OKFree for commercial use

Overview

Developer
Tencent AI4S
Commercial rights
Commercial OK
Commercial cost
Free commercially
Compute
Single GPU
Open weights
Yes
Last verified

Capabilities

Designs antibody sequences and structures together for a given antigen. Input: antigen structure plus the framework and the CDR positions to design; output: designed CDR sequences with the predicted antibody-antigen complex. Weights download automatically on first run.

When to use it

One of the few antibody design models whose weights are explicitly commercial-use-clear, so it belongs in any company pipeline as a cross-check against RFantibody and Germinal. Published validation is still largely in-silico.

Input / Output

Input
antigen structure plus the framework and the CDR positions to design
Output
designed CDR sequences with the predicted antibody-antigen complex

Compute

Single GPU. Other tools with this compute profile →

Commercial Licensing

Commercial rights — may a company use it?

Commercial use OK

Licence as writtenMIT License

MIT LICENSE (Copyright 2024, Tencent Inc.) and an unusually direct README statement: 'Our model and code are released under MIT License, and can be freely used for both academic and commercial purposes.' That sentence covers the weights as well as the code, which is rare in this field. Note the same group's tFold is non-commercial - do not assume the licence carries across repos.

The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.

Commercial cost — is commercial use free of charge?

Free for commercial use

Free: MIT, with the README stating free use for commercial purposes and weights fetched automatically at no charge.

Original sources — read on 15 Oct 2026
  1. raw.githubusercontent.com/TencentAI4S/IgGM/master/README.md

Price and rights are separate: this panel is about money, the panel above is about permission.

  • Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
  • Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
  • Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
  • Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.

Model Weights

Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.

Dependencies

Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.

Official References

Official site / repo
github.com/TencentAI4S/IgGM

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