La-Proteina
Partially latent flow-matching model generating sequence and all-atom structure jointly.
Developer: NVIDIA (BioNeMo)
Overview
- Developer
- NVIDIA (BioNeMo)
- Commercial rights
- Commercial OK
- Commercial cost
- Free commercially
- Compute
- Heavy GPU
- Open weights
- Yes
- Last verified
Capabilities
Generates a protein's sequence and full all-atom structure (backbone plus side chains) in one pass, including atomistic motif scaffolding. Input: length, or a motif with its atom coordinates; output: all-atom designs that do not need a separate inverse-folding step to get a sequence.
When to use it
Attractive when you want sequence and side chains out of the generator itself, especially for atomistic motif scaffolding. Check the Open Model License conditions with counsel; they are permissive but not as plain as MIT.
Input / Output
- Input
- length, or a motif with its atom coordinates
- Output
- all-atom designs that do not need a separate inverse-folding step to get a sequence
Compute
Heavy GPU. Other tools with this compute profile →
Commercial Licensing
Commercial rights — may a company use it?
Commercial use OKLicence as writtenApache License 2.0 (code); NVIDIA Open Model License Agreement (weights); separate dataset licence
This repo splits its licences into a LICENSE/ directory: license_code.txt is Apache-2.0, license_weights.txt is the NVIDIA Open Model License Agreement, and license_datasets.txt covers the data. The Open Model License is the permissive one NVIDIA uses to allow commercial use of model outputs and derivatives, in contrast to the plain 'NVIDIA License' on Proteina which is non-commercial - read the conditions (attribution, trustworthy-AI and no-reverse-engineering terms) before shipping.
The licence read at the source allows use by a company. Attribution or copyleft conditions may still apply — read the note.
Commercial cost — is commercial use free of charge?
Free for commercial useNo fee. Code Apache-2.0 and weights under the NVIDIA Open Model License, which grants use without payment subject to its conditions.
Price and rights are separate: this panel is about money, the panel above is about permission.
- Commercial OK ≠ Free of charge. A tool can be licensed for company use and still need a paid licence for a dependency (BindCraft → PyRosetta).
- Free download ≠ Commercially licensed. Weights you can download at no cost may still forbid commercial use (AlphaFold 3).
- Unverified ≠ Commercially permitted. If no published statement settles it, treat it as unknown — not as a yes.
- Every component counts. Each status considers the code licence, the model-weights terms, required dependencies and any terms of use.
Model Weights
Open weights. A separate weights licence is Not documented as its own field; where weights carry different terms from the code, that is stated in the licence explanation above.
Dependencies
Not documented as a separate field. Any dependency that affects commercial use (for example a paid PyRosetta licence) is named in the licence and cost explanations above.
Official References
- Official site / repo
- github.com/NVIDIA-BioNeMo/la-proteina
From the makers of FoldScout
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